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CDF Cellular Defense E™

Quantity: 60 ml / 2 floz

CDF Cellular Defense E™

Cellular Antioxidant for Long-Term Skin Defense

INCI Name: Water (Aqua), Propanediol, 1,2-Hexanediol, Ergothioneine

Appearance: Clear liquid

Solubility: Fully compatible with water-based systems; ideal for watery serums, gels, and emulsions

Typical Usage: 2–5%

Function: Cellular antioxidant defense, anti-fatigue support, pollution defense

CDF Cellular Defense E™ is a next-generation aqueous Ergothioneine concentrate engineered for modern “clean” and professional formulations. Ergothioneine is actively transported into cells via the OCTN1 transporter, offering intelligent, long-term antioxidant defense without the instability, discoloration, or formulation challenges common to many antioxidants.

Cellular Antioxidant OCTN1 Transport Anti-Fatigue Pollution Defense Water-Compatible Non-Discoloring

What It Does

Ergothioneine is one of the few cosmetic antioxidants with a dedicated cellular uptake pathway. Skin cells can actively transport Ergothioneine via the OCTN1 transporter, allowing it to accumulate where oxidative stress occurs, rather than remaining surface-bound. This makes it a uniquely effective “smart antioxidant” for long-term skin defense.

Key Benefits

  • Provides cellular-level antioxidant protection through OCTN1-mediated uptake
  • Helps defend against pollution-induced oxidative stress and daily environmental exposure
  • Supports a more rested, resilient skin appearance (anti-fatigue positioning)
  • Highly stable in aqueous systems and does not discolor over time
  • Ideal for modern minimalist formulas and advanced “urban defense” systems

Performance Profile

CDF Cellular Defense E™ is designed for daily, cumulative protection rather than instant cosmetic effects. It supports long-term cellular resilience against oxidative stress with consistent use at effective inclusion levels.

Suggested Use Level

  • Use 2–5% in finished formulas
  • Add during cool-down (≤40 °C)

Formulation Guidelines

  • Designed for watery serums, hydrogels, essences, and emulsions.
  • Mixes cleanly into water phases; add during cool-down for best handling.
  • Recommended finished-formula pH range: ~4.5–7.0.
  • Compatible with niacinamide, panthenol, ectoin, hyaluronic acid, peptides, and most botanical extracts.
  • Unlike many antioxidants, Ergothioneine is highly stable and typically does not cause yellowing or browning.

Common Applications

  • Anti-pollution / urban defense serums
  • Daily antioxidant protection products
  • Anti-fatigue skincare
  • Barrier-support and recovery formulas
  • Watery gels, essences, and lightweight emulsions

Documents

  • Certificate of Analysis (COA)
  • Safety Data Sheet (SDS)

Disclaimer

This ingredient is supplied strictly as a cosmetic raw material. It is not intended for direct application to the skin without proper formulation. Not a drug or medicinal ingredient. Not evaluated for therapeutic, dermatological, or pharmaceutical use. For use by trained formulators and manufacturers only.

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