INCI Name: N-Acetyl Glucosamine
Appearance: White crystalline powder
Solubility: Water-soluble
Usage Rate: 1% – 5%
Function: Brightening, exfoliating, hydrating, barrier-repair
N-Acetylglucosamine (NAG) is a gentle, non-acidic exfoliant and skin-brightening active that improves skin tone, texture, and hydration. A naturally occurring amino sugar, it’s clinically shown to fade dark spots, boost hyaluronic acid production, and enhance niacinamide performance.
NAG is a mild yet powerful alternative to AHAs. It encourages gentle exfoliation, visibly brightens hyperpigmented areas, and supports the skin’s natural production of hyaluronic acid. It is especially effective when paired with niacinamide and is safe for daily use, even on sensitive skin.
COA
SDS
NAG inhibits tyrosinase activity and melanin production, particularly when paired with Niacinamide. The synergy of these two actives is well-documented in clinical studies for reducing hyperpigmentation and improving uneven tone.
Together they work on different steps of the pigmentation pathway: NAG decreases melanin synthesis, while Niacinamide prevents melanin transfer to skin cells. This dual mechanism delivers faster and more reliable brightening results.
Yes. NAG is a building block of hyaluronic acid and can stimulate its production in the skin. This makes it both a brightening agent and a hydration booster, improving plumpness and barrier function.
Yes, it pairs well with exfoliants. While acids resurface the skin, NAG works on pigment regulation and barrier reinforcement, reducing the risk of irritation that strong acids may cause.
NAG can reduce the appearance of fine lines by stimulating natural hyaluronic acid production and improving extracellular matrix integrity. It also has mild exfoliating effects that support smoother skin texture.
Yes. NAG has been shown to reduce sebum production and improve post-inflammatory hyperpigmentation, making it a useful addition to acne-prone skin regimens.
Most users notice improvements in hydration and skin smoothness within 2–4 weeks, while visible brightening and reduction in dark spots typically appear in 8–12 weeks of consistent use.
NAG is relatively stable in water-based formulations and tolerates combinations with Niacinamide, peptides, and mild acids. However, very low pH systems (strong AHAs below pH 3.5) may reduce stability.
Yes. The two ingredients complement each other by targeting pigmentation through different pathways. Tranexamic Acid helps block pigment transfer and calm inflammation, while N-Acetylglucosamine reduces melanin synthesis and boosts hyaluronic acid production for added hydration. Used together, they deliver stronger results on melasma, post-inflammatory hyperpigmentation, and uneven skin tone without the harshness of hydroquinone. For even greater effectiveness, NAG also pairs exceptionally well with Niacinamide, creating a triple-action system with Tranexamic Acid that tackles discoloration, barrier repair, and hydration in one routine.
